Table 3. Concentrations of cytokines in skin tissue as determined by ELISA.

Group	IFN-γ	TNF-α	IL-17A	IL-23
Control A	3,688.5±649.4**	4,134±326.9**	184±31.3**	408.6±57.5**
Model B	5,997±711.4	5,602.2±489.4	258.1±22.5	633.9±69.4
Treatment C1	5,757.6±742.7	5,028.2±544.7**	252.2±30.9	576.9±34.4**
Treatment C2	5,101.7±837.7**	4,531.9±358.3**	248.5±34.2**	580.3±69.1**
Treatment C3	4,752.5±658.1**	4,571.3±643.3**	227.9±33.0**	546.9±89.1**
Fresh D	3,869.9±840.1**	4,289.2±542.9**	203.7±28.1**	458.9±71.4**

Concentrations of IFN-γ, TNF-α, IL-17A and IL-23 in the skin of each group were measured by ELISA on the 7th day after the death of each group of mice, and the data are the mean ± labeling difference of 3 independent experiments ($\overline{x}\pm s$, n=10). **, P<0.01 indicates a very significant difference compared with model group B. ELISA, enzyme-linked immunosorbent assay; IFN, interferon; TNF, tumor-necrosis factor; IL, interleukin.