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. 2021 Dec 29;8(6):554–561. doi: 10.14744/nci.2021.24865

Table 2.

The reported frequency of the atypical chest computed tomography findings

Current study Zarifian et al. (metaanalysis) [16] Li et al. [20] Wu et al. [21] Pakdemirli et al. [22] Wang et al. [23] Tabatabaei et al. [24] Werberich et al. [25]
Number of patients (n=414) (n=9907) (n=83) (n=80) (n=18) (n=93) (n=120) (n=48)
Pleural thickening and/or effusion 16.9 5345–741 (13.8%) 8.4 6 88 31.1 16.6 4.2
Nodule 5.7 2582–338 (13.1%) 7.2 61 18.3 25 4.2
Reversed halo sign 1.2 0 15.1 11.6 4.2
LAP 2.1 3197–165 (5.1%) 8.4 4 17 6.5 0 4.2
Pericardial effusion 1.6 4.8 5 6.2
Subpleural line 0.9 20.5 20 61 14.6
Subpleural sparing 3.3 33 23.3 6.2
Spider web sign 2.8 25.3 25
Air bubble sign 13 (3.1%) 12.9 37.5
Tree-in-bud 4 (0.9%) 6 3.2 0
Central and/or 1.9 2160–131 (6.1%) 4 11 2.1
peribronchovascular involvement
Isolated upper lobe involvement 3.8 0 10.4

LAP: Lymphadenopathy.