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. 2022 Feb 8;17(9):1991–1997. doi: 10.4103/1673-5374.335162

Figure 5.

Figure 5

Effect of SGB on inflammation in ischemic stroke diabetic rats (enzyme-linked immunosorbent assay).

(A) Effect of nighttime SGB on inflammatory cytokines in plasma of ischemic stroke diabetic rats. (B) Quantitative analysis of IL-6, IL-1β, and TNF-α levels in plasma. The data are presented as the mean ± SD (n = 6). *P < 0.05, vs. Sham group; #P < 0.05, vs. SGB daytime group; &P < 0.05, vs. MCAO + SGB + TAK242 group; †P < 0.05, vs. MCAO + SGB + LPS group (one-way analysis of variance followed by the Student-Newman-Keuls post hoc test). IL-6: Interleukin-6, IL-1β: interleukin-1β; LPS: Lipopolysaccharide, a TLR4 agonist; MCAO: middle cerebral artery occlusion; NF-κB: nuclear factor kappa-B; SGB: stellate ganglion block; TAK-242 (Resatorvid): a small-molecule-specific inhibitor of TLR4 signaling; TLR4: Toll-like receptor 4; TNF-α: tumor necrosis factor-α.