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Effects of MCAO and SGB on 48-hour survival in rats
| Group | SGB daytime | MCAO+SGB+LPS | MCAO+SGB+TAK242 |
|---|---|---|---|
| Survive | 12† | 12 | 12 |
| Total | 17 | 26 | 16 |
| 48-h survival rate (%) | 70.59 | 46.15 | 75 |
†P < 0.05, vs. MCAO + SGB + LPS group (Student’s t-test). LPS: Lipopolysaccharide, a Toll-like receptor agonist; MCAO: middle cerebral artery occlusion; SGB: stellate ganglion block; TAK-242 (Resatorvid): a smallmolecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling.
