Figure 5.
Urolithin A ameliorates neurological deficits following traumatic brain injury.
(A) mNSS score was calculate at 1, 3, 7, and 14 days following TBI (n = 15). (B) Rotarod tests were performed before TBI and 1, 3, 7, 14 days following TBI, and latencies to falls were recorded to assess motor and balance deficits (n = 15). Data are represented as mean ± SD. **P < 0.01, ***P < 0.001, vs. TBI + Ve group (one-way analysis of variance followed by Bonferroni's post hoc test). mNSS: Modified neurological severity score; n.s.: no statistical significance between indicated groups; TBI: traumatic brain injury; UA: urolithin A; Ve: vehicle.