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Effect of Honokiol on mitochondrial ROS generation and oxidative stress in ATO‐treated hearts. Honokiol attenuated ATO‐induced increase in ROS (H2O2) production in isolated heart mitochondria, as measured by Amplex Red (A), ROS generation in whole tissue lysates of hearts from each group was measured by DCFDA using fluorescence plate reader (B). The data are expressed as means ± SD, n = 6–8, *p < .05 versus vehicle in sham; # p < .05 versus vehicle in ATO‐exposed mice
