Table 1.

Nearest-neighbor parameters for DNA/DNA duplexes

Nearest-neighbor sequence	$\mathrm{\Delta }{G}_{37}^{\circ }$
$(5^{\prime }\to 3^{\prime }/3^{\prime }\to 5^{\prime })$	(kJ × mol−1
AA/TT	−4.26
AT/TA	−3.67
AC/TG	−6.09
AG/TC	−5.40
TA/AT	−2.50
TC/AG	−5.51
TG/AC	−6.12
CG/GC	−9.07
GC/CG	−9.36
CC/GG	−7.66
Terminal A/T	4.31
Terminal C/G	4.05