Fig. 13. (A) Single-stranded DNA was used to guide the voltage-driven capture of a DNA-origami nanoplate (red cylinders) at the opening of a SiN nanopore. Nanoplates containing a terminal single-stranded DNA strand could be used to detect the binding of complementary sequences.61 (B) Top-down view of the nanoplate. The size of the opening can be controlled by the design of the sequences used to assemble the nanoplate.61 (C) Voltage-driven capture of a DNA nanosphere (red) in a lipid-coated SiN nanopore enabled the electro-osmotic trapping (dashed lines) and detection of several different proteins (blue).62.
