Table 2.
Two-Way ANOVA Analysis of MTT Proliferation Assay on Endothelial Cells and Perivascular Fibroblasts Grown on Plastic versus GO-3D Mesha
| I. comparison: plastic versus GO-3D | ||
| interaction (condition × time) | growth condition | time in culture |
| (Dfn = 1, Dfd = 24) | (Dfn = 1, Dfd = 24) | (Dfn = 2, Dfd = 24) |
| EC2500 12.85%, F = 11.61, p = 0.003 | 11.7%, F = 21.15, p = 0.0001 | 62.15%, F = 56.13, p < 0.0001 |
| EC5000 23.53%, F = 55.87, p < 0.0001 | 8.49%, F = 40.3, p < 0.0001 | 62.93%, F = 144.44, p < 0.0001 |
| Fb2500 6.73%, F = 3.09, p = 0.0638 | 0.71%, F = 0.65, p = 0.4269 | 66.47%, F = 30.57, p < 0.0001 |
| Fb5000 8.53%, F = 4.72, p = 0.0186 | 3.75%, F = 4.15, p = 0.0528 | 66.04%, F = 36.57, p < 0.0001 |
| II. comparison: plastic-adherent (same well) versus GO-3D | ||
| interaction (condition × time) | growth condition | time in culture |
| (Dfn = 1, Dfd = 24) | (Dfn = 1, Dfd = 24) | (Dfn = 2, Dfd = 24) |
| EC2500 24.71%, F = 35.41, p < 0.0001 | 59.33%, F = 170.04, p < 0.0001 | 7.59%, F = 10.88, p = 0.0004 |
| EC5000 38.07%, F = 55.87, p < 0.0001 | 34.61%, F = 132.49, p < 0.0001 | 21.05%, F = 40.29, p < 0.0001 |
| Fb2500 14.06%, F = 6.54, p = 0.0054 | 23.61%, F = 21.96, p < 0.0001 | 36.54%, F = 17.00, p < 0.0001 |
| Fb5000 10.89%, F = 8.26, p = 0.0019 | 44.26%, F = 67.10, p < 0.0001 | 29.02%, F = 22.00, p < 0.0001 |
a
Data are reported as % variance with the F ratio, degrees of freedom for the numerator (Dfn) and the denominator (Dfd), and the calculated p value for each of the two variables (growth condition and time in culture) and are linked to the results in Figure 7 and Figure 8.