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. 2022 Feb 16;10(1):e01671-21. doi: 10.1128/spectrum.01671-21

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Copyright © 2022 Kovacs-Kasa et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 4 — Cytokine profiling of SARS-CoV-2 patient plasma. Inflammatory cytokine levels were analyzed in 8 SARS-CoV-2 patients’ plasma samples in duplicate; 25 μL plasma was analyzed in the assay, using the Milliplex High Sensitivity Human Cytokine Panel (MILLIPLEX MAP– Premixed 15 Plex, EMD Millipore). (A) TNF-α, (B) IFNγ, (C) IL-10, (D) IL-6, (E) IL-17A, (F) GM-CSF, (G) IL-21, (H) IL-12p70, (I) IL-8, (J) MIP1α, (K) IL-1β, (L) IL-13, (M) IL-7, (N) IL-4, (O) IL-2. Commercially available normal pooled plasma was used as the normal plasma group control, shown by mean and SEM. The dashed line shows the level of each cytokine in the normal plasma samples. n = 3.