Table 1.
Clinical, demographic and radiological characteristics of patients with/without discordant T2/FLAIR T1CE images.
| Characteristics | Discordant | Accordant | P-value |
|---|---|---|---|
| Number of patients | 44 (25.9%) | 126 (74.1%) | - |
| Age at diagnosis (years) | |||
| Mean | 46.3 ± 12.8 | 49.6 ± 12.1 | 0.130 |
| Median | 50.0 | 51.0 | 0.847 |
| Gender | |||
| Male | 30 (68.2%) | 85 (67.5%) | 0.930 |
| Female | 14 (31.8%) | 41 (32.5%) | |
| Preoperative KPS | |||
| >70 | 36 (81.8%) | 81 (64.3%) | 0.031 |
| ≤ 70 | 8 (18.2%) | 45 (35.7%) | |
| Extent of resection | |||
| GTR | 32 (72.7%) | 64 (50.8%) | 0.012 |
| Non-GTR | 12 (27.3%) | 62 (49.2%) | |
| Tumor volume (cm3) | |||
| Mean | 36.8 ± 33.1 | 44.5 ± 51.7 | 0.352 |
| Median | 31.7 | 38.0 | 0.330 |
| Ventricle infringement | |||
| Yes | 23 (52.3%) | 79 (62.7%) | 0.224 |
| No | 21 (47.7%) | 47 (37.3%) | |
| MGMT promoter | |||
| Methylated | 19 (43.2%) | 44 (35.8%) | 0.384 |
| Unmethylated | 25 (56.8%) | 79 (64.2%) | |
| Tumor location | |||
| Frontal | 13 (29.5%) | 41 (32.5%) | 0.926 |
| Temporal | 16 (36.4%) | 40 (31.7%) | |
| Insular | 9 (20.5%) | 22 (17.5%) | |
| Parietal | 4 (9.1%) | 16 (12.7%) | |
| Occipital | 2 (4.5%) | 7 (5.6%) | |
| TERT promoter | |||
| Mutant | 11 (37.5%) | 49 (42.3%) | 0.080 |
| Wild | 17 (62.5%) | 35 (57.7%) | |
| Patterns of progression | |||
| Local recurrence | 24 (54.5%) | 103 (81.7%) | 0.003 |
| Distant metastasis | 9 (20.5%) | 8 (6.3%) | |
| Subependymal spread | 9 (20.5%) | 11 (8.7%) | |
| Leptomeningeal dissemination | 2 (4.5%) | 4 (3.2%) |
T1CE, T1 weighted contrast-enhancing images; KPS, Karnofsky Performance Status score; GTR, gross total removal of tumor; MGMT, O-6-methylguanine DNA methyltransferase. Bold: significant.