Table III.
Perinatal outcomes in women with different ICM grades.
| Perinatal outcomes | Grade A (n = 1356) | Grade B (n = 5704) | Grade C (n = 409) |
|---|---|---|---|
| PTD | 125 (9%) | 546 (10%) | 45 (11%) |
| (Crude OR) | (Reference) | 1.04 (0.85, 1.28) | 1.22 (0.85, 1.75) |
| (Adjusted OR) | (Reference) | 1.05 (0.85, 1.32) | 1.23 (0.86, 1.79) |
| VPTD | 29 (2%) | 125 (2%) | 8 (2%) |
| (Crude OR) | (Reference) | 1.03 (0.68, 1.54) | 0.91 (0.41, 2.01) |
| (Adjusted OR) | (Reference) | 0.97 (0.63, 1.50) | 0.89 (0.40, 1.96) |
| Female newborn | 612 (45%) | 2509 (44%) | 145 (35%) |
| (Crude OR) | (Reference) | 0.95 (0.85, 1.08) | 0.67 (0.53, 0.84) |
| (Adjusted OR) | (Reference) | 0.83 (0.73, 0.95) | 0.63 (0.50, 0.79) |
| C-section | 875 (66%) | 3824 (69%) | 279 (71%) |
| (Crude OR) | (Reference) | 1.15 (1.01, 1.31) | 1.25 (0.98, 1.60) |
| (Adjusted OR) | (Reference) | 1.11 (0.97, 1.27) | 1.22 (0.95, 1.57) |
| LBW | 53 (4%) | 241 (4%) | 16 (4%) |
| (Crude OR) | (Reference) | 1.08 (0.80, 1.47) | 0.99 (0.56, 1.76) |
| (Adjusted OR) | (Reference) | 1.06 (0.76, 1.46) | 0.98 (0.55, 1.74) |
| Macrosomia | 137 (10%) | 627 (11%) | 63 (15%) |
| (Crude OR) | (Reference) | 1.10 (0.90, 1.33) | 1.61 (1.17, 2.22) |
| (Adjusted OR) | (Reference) | 1.12 (0.91, 1.38) | 1.66 (1.20, 2.30) |
| SGA | 44 (3%) | 224 (4%) | 14 (3%) |
| (Crude OR) | (Reference) | 1.22 (0.88, 1.69) | 1.05 (0.57, 1.93) |
| (Adjusted OR) | (Reference) | 1.09 (0.77, 1.55) | 1.02 (0.55, 1.88) |
| LGA | 254 (19%) | 1242 (22%) | 103 (25%) |
| (Crude OR) | (Reference) | 1.21 (1.04, 1.40) | 1.45 (1.11, 1.88) |
| (Adjusted OR) | (Reference) | 1.23 (1.05, 1.45) | 1.47 (1.12, 1.92) |
| PPROM | 16 (1%) | 83 (1%) | 6 (1%) |
| (Crude OR) | (Reference) | 1.24 (0.72, 2.12) | 1.25 (0.48, 3.21) |
| (Adjusted OR) | (Reference) | 1.43 (0.81, 2.52) | 1.38 (0.53, 3.57) |
| GDM | 136 (10%) | 614 (11%) | 43 (11%) |
| (Crude OR) | (Reference) | 1.08 (0.89, 1.32) | 1.05 (0.73, 1.51) |
| (Adjusted OR) | (Reference) | 1.15 (0.93, 1.42) | 1.07 (0.73, 1.55) |
| GHD | 45 (3%) | 215 (4%) | 18 (4%) |
| (Crude OR) | (Reference) | 1.14 (0.82, 1.58) | 1.34 (0.77, 2.33) |
| (Adjusted OR) | (Reference) | 1.11 (0.78, 1.58) | 1.32 (0.74, 2.35) |
Adjusted with female age, female BMI, primary infertility, parity, reason for IVF and assisted hatching, blastocyst development stage status and TE quality. The values in bold are statistically significant.
GDM, gestational diabetes mellitus; GHD, gestational hypertensive disease; LBW, low birth weight; LGA, large for gestational age; OR, odds ratio; PPROM, preterm premature rupture of membrane; PTD, preterm delivery; SGA, small for gestational age; TE, trophectoderm; VPTD, very preterm delivery.