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. 2021 Oct 30;2021(4):hoab036. doi: 10.1093/hropen/hoab036

Table IV.

Perinatal outcomes in women with different TE grades.

Perinatal outcomes Grade A (n = 818) Grade B (n = 5116) Grade C (n = 1525)
PTD 88 (11%) 497 (10%) 141 (9%)
(Crude OR) (Reference) 0.87 (0.68, 1.11) 0.85 (0.64, 1.12)
(Adjusted OR) (Reference) 0.86 (0.67, 1.11) 0.84 (0.63, 1.14)
VPTD 23 (3%) 101 (2%) 38 (2%)
(Crude OR) (Reference) 0.69 (0.44, 1.10) 0.88 (0.52, 1.49)
(Adjusted OR) (Reference) 0.72 (0.45, 1.19) 0.94 (0.54, 1.64)
Female newborn 311 (38%) 2174 (43%) 781 (51%)
(Crude OR) (Reference) 1.20 (1.03, 1.40) 1.71 (1.44, 2.03)
(Adjusted OR) (Reference) 1.30 (1.11, 1.53) 1.88 (1.57, 2.26)
C-section 535 (67%) 3409 (69%) 1034 (71%)
(Crude OR) (Reference) 1.08 (0.92, 1.26) 1.20 (0.99, 1.44)
(Adjusted OR) (Reference) 1.02 (0.87, 1.21) 1.14 (0.94, 1.39)
LBW 41 (5%) 201 (4%) 68 (5%)
(Crude OR) (Reference) 0.77 (0.55, 1.09) 0.89 (0.60, 1.32)
(Adjusted OR) (Reference) 0.76 (0.53, 1.09) 0.89 (0.58, 1.35)
Macrosomia 80 (10%) 594 (12%) 153 (10%)
(Crude OR) (Reference) 1.21 (0.95, 1.55) 1.03 (0.76, 1.37)
(Adjusted OR) (Reference) 1.10 (0.85, 1.43) 0.95 (0.70, 1.27)
SGA 23 (3%) 188 (4%) 71 (5%)
(Crude OR) (Reference) 1.31 (0.85, 2.04) 1.69 (1.05, 2.72)
(Adjusted OR) (Reference) 1.33 (0.84, 2.12) 1.74 (1.05, 2.88)
LGA 166 (21%) 1118 (22%) 315 (21%)
(Crude OR) (Reference) 1.09 (0.91, 1.31) 1.02 (0.83, 1.26)
(Adjusted OR) (Reference) 1.02 (0.84, 1.23) 0.96 (0.77, 1.20)
PPROM 11 (1%) 78 (1%) 16 (1%)
(Crude OR) (Reference) 1.13 (0.60, 2.14) 0.78 (0.36, 1.68)
(Adjusted OR) (Reference) 1.06 (0.55, 2.04) 0.63 (0.28, 1.42)
GDM 108 (13%) 540 (10%) 145 (9%)
(Crude OR) (Reference) 0.77 (0.62, 0.97) 0.69 (0.53, 0.90)
(Adjusted OR) (Reference) 0.74 (0.59, 0.94) 0.67 (0.50, 0.88)
GHD 31 (4%) 189 (4%) 58 (4%)
(Crude OR) (Reference) 0.97 (0.66, 1.43) 1.00 (0.64, 1.56)
(Adjusted OR) (Reference) 0.94 (0.62, 1.42) 0.97 (0.60, 1.57)

Adjusted with female age, female BMI, primary infertility, parity, reason for IVF and assisted hatching, blastocyst development stage status and ICM quality. The values in bold are statistically significant.

GDM, gestational diabetes mellitus; GHD, gestational hypertensive disease; ICM, inner cell mass; LBW, low birth weight; LGA, large for gestational age; OR, odds ratio; PPROM, preterm premature rupture of membrane; PTD, preterm delivery; SGA, small for gestational age; TE, trophectoderm; VPTD, very preterm delivery.