Figure 1.

Patients With COVID-19 Infection Have Impaired Endothelial Function

(A) Microvascular digital endothelial function expressed as reactive hyperemia index (RHI) in healthy subjects (n = 14) and patients with COVID-19 in the acute phase of the infection (n = 15) and at follow-up (FU) 4 months later (n = 10). (B) RHI in a subgroup of patients with COVID-19 evaluated both in the acute phase of the infection and at follow-up 4 months later (n = 10 each). Significant differences were analyzed using 1-way analysis of variance (ANOVA) and Tukey’s multiple comparison post hoc test in A and paired Student's t-test in B; ∗∗P < 0.01, ∗∗∗P < 0.001 vs healthy. Values are expressed as mean ± SD (A) or individual dot plots (B).