Table 2. Association between MEG3 and HOTAIR expression with the clinicopathological features in patients with GC.
| Clinical parameter | No. of cases | Expression means of MEG3 (fold change) |
P-value | Expression means of HOTAIR (fold change) |
P-value |
|---|---|---|---|---|---|
| Age | 0.727 | 0.206 | |||
| ≤50 | 50 | 22.15 | 10.07 | ||
| >50 | 50 | 17.49 | 6.04 | ||
| Gender | 0.752 | 0.400 | |||
| Male | 37 | 33.92 | 12.13 | ||
| Female | 63 | 10.02 | 5.22 | ||
| Metastasis | 0.688 | 0.641 | |||
| Yes | 43 | 15.09 | 4.94 | ||
| No | 57 | 23.39 | 10.40 | ||
| Size | 0.331 | 0.017 | |||
| ≥5 cm | 42 | 21.64 | 8.56 | ||
| <5 cm | 58 | 18.21 | 7.60 | ||
| Stage | 0.593 | 0.031 | |||
| I, II | 50 | 17.21 | 9.07 | ||
| III, IV | 50 | 22.65 | 6.96 | ||
| H. Pylori | 0.013 | 0.001 | |||
| Positive | 55 | 17.68 | 6.66 | ||
| Negative | 45 | 24.58 | 11.16 |