Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 2;8:787225. doi: 10.3389/fnut.2021.787225

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Lin, Weibel, Landolt, Santini, Garbazza, Kistler, Rehm, Rentsch, Borgwardt, Cajochen and Reichert.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Associations of habitual daily intake and half-lives of caffeine and paraxanthine. (A,B) The negative association between habitual self-reported caffeine intake (mg/kg/day) and the half-life of caffeine and paraxanthine in the caffeine condition, respectively. (C) The association between habitual caffeine intake (mg/kg/day) and the ratio of AUC of paraxanthine (AUC-PX) to AUC of CA (AUC-CA). In (C) a high ratio of AUC-PX to AUC-CA indicates a larger disproportional accumulation between paraxanthine and caffeine.