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. 2022 Jan 5;11:e73358. doi: 10.7554/eLife.73358

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© 2022, Hansen et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 2. — (A) The number of tissue-specific genes predicted from the hypergeometric distribution to be activated by FOXA1 compared to the number actually activated. Liver enrichment (p<10^–4) is significant. There are 242 total liver-enriched genes. (B) The number of tissue-specific genes predicted from the hypergeometric distribution to be activated by HNF4A compared to the number actually activated. Liver- (p<10^–8) and intestine enrichment (p<10^–15) are significant. There are 242 total liver-enriched genes and 122 total intestine-enriched genes. (C) 242 liver genes characterized as activated by Foxa1, HNF4A, both, or neither. (D) 122 intestine genes characterized as activated by FOXA1, HNF4A, both, or neither.