Table 2.

Univariate and multivariate linear regression analyses for factors associated with QTc interval

	Unadjusted linear regression analysis		Adjusted linear regression analysis
Variable	β coefficient (95% CI)	p value	β coefficient (95% CI)	p value
Age in years	0.25 (−0.001 to 0.51)	0.050	0.09 (−0.17 to 0.35)	0.491
Female sex	15.52 (10.29–20.61)	<0.001	15.26 (7.58–22.94)	<0.001
BMI in kg/m2	0.31 (−0.14 to 0.76)	0.182
Waist circumference in cm	0.09 (−0.09 to 027)	0.334
Duration of diabetes in years	0.38 (−0.04 to 0.80)	0.074	0.18 (−0.75 to 0.39)	0.532
Fasting blood sugar in mmol/L	−0.06 (−0.57 to 0.46)	0.832
HbA1c (%)	−0.07 (−1.04 to 0.89)	0.887
History of hypertension	7.39 (2.02–12.76)	0.007
Resting systolic blood pressure in mmHg	0.18 (0.07–0.29)	0.002
Resting diastolic blood pressure in mmHg	0.41 (0.18–0.64)	0.001
Mean arterial pressure in mmHg	0.34 (0.16–0.53)	<0.001	0.34 (0.07–0.63)	0.019
Pulse pressure in mmHg	0.14 (−0.01 to 0.28)	0.057
Antihypertensive drugs
None	Ref		Ref
Diuretic	11.72 (−4.25 to 27.69)	0.149	10.07 (−4.97 to 25.11)	0.187
ACEI/ARB	11.77 (−0.69 to 24.23)	0.064	10.70 (−1.19 to 22.58)	0.077
Beta blocker	8.63 (−9.23 to 26.50)	0.341	4.55 (−13.09 to 22.19)	0.611
Calcium channel blocker	17.34 (4.97–29.72)	0.006	14.65 (−0.67 to 26.57)	0.054

CI confidence interval, BMI body mass index, HbA1c glycosylated hemoglobin, ARB angiotensin receptor blocker, ACEI angiotensin-converting enzyme inhibitor, Ref reference category