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. Author manuscript; available in PMC: 2023 Feb 3.
Published in final edited form as: Mol Cell. 2022 Jan 19;82(3):616–628.e5. doi: 10.1016/j.molcel.2021.12.021

Figure 5. Type I-F3 CRISPR-Tn systems carry diverse bacterial defense systems as cargo.

Figure 5.

The native genomic layout of a subset of CRISPR-Tn homologs is shown. Transposons are highlighted with a light blue box and shown with the right (R) end on the right side of the figure. Transposition and DNA targeting modules are shown in yellow and blue, respectively. Putative defense systems are highlighted in red when the complete gene set was found. Roman numerals in brackets indicate the predicted subtype of the defense system. A large diversity of defense systems are found, suggesting that CRISPR-Tn systems provide a benefit to bacterial hosts by providing innate immunity from phage predation. See also Figure S5.