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. 2022 Feb 9;602(7897):510–517. doi: 10.1038/s41586-022-04398-6

Extended Data Fig. 2. De novo signatures of DBS and MBS signatures.

Extended Data Fig. 2

a, The activity of DBS de novo signatures (top) and the corresponding signatures extracted from prostate, skin, stomach, and uterine cancers that could not be accurately reconstructed using known COSMIC mutational signatures (bottom; Methods). b, The activity of MBS de novo signatures (top) and the corresponding signatures extracted from colon, oesophagus, and head and neck cancers that could not be accurately reconstructed using known COSMIC mutational signatures (bottom; Methods).