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. 2022 Jan 10;96(3):691–710. doi: 10.1007/s00204-021-03212-y

Fig. 3.

Fig. 3

Evolution of in vitro model of complex tissue. A, B Early liver spheroid culture (Mueller et al. 2014); C, D liver spheroid culture for in situ quantification (Hong and Song 2021); EH 3D printed vascularized liver model (Massa et al. 2017)