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. 2022 Feb 1;96(3):743–766. doi: 10.1007/s00204-021-03215-9

Table 1.

Dose level limits derived from CPL used in setting exposure categories

Cat 1 Cat 2 Cat 3 Cat 4 Cat 5
Acute Oral (ATE)  < 5 5–50 50–300 300–2000  > 2000
STOT-SE (NOAEL)  < 300 300–2000 2000–5000  > 5000
Dermal Sens (Conc)  < 0.1% 0.1–10% 10–100% No response
STOT-RE (NOAEL)  < 10 10–100 100–1000  > 1000
Carcinogenicity SCL (T25)  < 1 1–100  > 100 No response
Repro SCL (ED10)  < 4 4–400  > 400 No response

The values are the dose levels from laboratory animal studies in mg/kg/day