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. 2022 Feb 1;96(3):743–766. doi: 10.1007/s00204-021-03215-9

Table 2.

Exposure category limits. *Category E is based on the TTC and would vary depending on the genotoxicity and Cramer class of the chemical

Cat A (mg/kg) Cat B (mg/kg) Cat C Cat D Cat E* (μg/kg)
1 day  > 50 20–50 3–20 mg/kg 0.0025 μg/kg–3 mg/kg  < 0.0025
Intermittent/short term  > 10 4–10 40 μg/kg–4 mg/kg 0.0025–40 μg/kg  < 0.0025
Long term  > 10 1–10 10 μg/kg–1 mg/kg 0.0025–10 μg/kg  < 0.0025