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CD44 expression in pan-glioma subtypes. Expression of CD44 is elevated in LGr4 among pan-glioma transcriptome subtypes (A), in LGm4 and LGm5 among pan-glioma DNA methylation subtypes (C) and in classic–like, mesenchymal–like, and LGm6–GBM among supervised pan-glioma subtypes (E). These distinct glioma subtypes with high CD44 expression are in bad clinical outcomes (B,D,F). Tested by t-test: ***p < 0.001; **p < 0.01; ns, p ≥ 0.05.
