Table 1.

Multi-variate Cox-regression analysis of CD44 expression with Age and Gender.

Dataset	Group	HR	95%CI	p
TCGA	All	1.5361	1.3669–1.726	5.68e-13	***
	WHO II	1.515	1.0482–2.189	0.0271	*
	WHO III	1.3258	1.0868–1.617	0.00543	**
	WHO IV	1.1447	0.9519–1.377	0.151
	IDH mutant	1.2393	0.9928–1.547	0.057922
	IDH wildtype	1.2441	1.0719–1.444	0.00406	**
	1p19q codeletion	1.487	0.9152–2.416	0.109
	1p19q Non-codeletion	1.3618	1.1942–1.553	4.03e-06	***
CGGA	All	1.2832	1.2107–1.360	0	***
	WHO II	1.191	1.0026–1.415	0.0467	*
	WHO III	1.2822	1.1580–1.420	1.73e-06	***
	WHO IV	1.1233	1.0368–1.217	0.00448	**
	IDH mutant	1.3049	1.1815–1.441	1.52e-07	***
	IDH wildtype	1.1274	1.0453–1.216	0.00188	**
	1p19q codeletion	1.26	0.9945–1.596	0.0556
	1p19q Non-codeletion	1.2018	1.1230–1.286	1.07e-07	***
	MGMT methylation	1.236	1.1297–1.352	3.78e-06	***
	MGMT Un-methylation	1.374	1.2460–1.514	1.79e-10	***
	Primary tumor	1.329	1.2164–1.451	2.69e-10	***
	Recurrent tumor	1.1573	1.0720–1.249	0.000184	***

HR, hazard ratio; CI, confidence interval;

^***p < 0.001,

^**p < 0.01,

^*p < 0.05.