TABLE 1.
Area under the curve and cut-off values of receiver operating characteristic curve for prediction of thrombocytopenia in neonates on LZD treatment.
| Risk factors | AUC (95%confidence interval) | pvvalue | Cut-off point | Youden’s index | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|
| Weight at medication (g) | 0.679 (0.621–0.736) | 0.000 | 2365.0 | 0.269 | 34.8 | 92.1 |
| Gestational age (w) | 0.715 (0.662–0.768) | 0.000 | 32.8 | 0.324 | 51.2 | 81.2 |
| PLT (×109/L) | 0.605 (0.550–0.660) | 0.000 | 233.5 | 0.222 | 47.0 | 75.2 |
| Duration of LZD treatments (d) | 0.600 (0.527–0.673) | 0.004 | 14.5 | 0.235 | 33.3 | 90.2 |
| Predicted probability | 0.873 (0.832–0.914) | 0.000 | 0.2 | 0.586 | 84.4 | 74.2 |
AUC, area under the curve; PLT, platelet; LZD, linezolid.