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. 2022 Feb 3;13:710099. doi: 10.3389/fphar.2022.710099

TABLE 2.

General clinical data of patients.

Characteristics Value LIT group (n = 9) Non-LIT group (n = 30) T/Z p value
Gender
Female, n (%) 14 (35.9) 4 (44.4) 10 (33.3) 0.696
Male, n (%) 25 (64.1) 5 (55.6) 20 (66.7)
GA (w), (mean ± SD) 31.3 ± 3.7 28.8 ± 3.3 32.0 ± 3.5 −2.463 0.019
PNA (d), median (IQR) 12.0 (7.0, 20.0) 10.0 (3.0, 26.5) 12.5 (8.8, 19.3) −0.818 0.413
BW (g), median (IQR) 1350.0 (1000.0, 1850.0) 880.0 (760.0, 1360.0) 1525.0 (1200.0, 1900.0) −2.836 0.005
Weight at medication (g), median (IQR) 1560.0 (1190.0, 1990.0) 840.0 (745.0, 1785.0) 1630.0 (1295.0, 2075.0) −2.584 0.008
Duration of LZD treatments (d), median (IQR) 10.0 (9.0,12.0) 12.0 (8.0, 14.0) 10.0 (8.8, 11.0) −1.197 0.231
PLT (×109/L), median (IQR) 206.0 (169.0, 267.5) 236.0 (139.0, 312.0) 201.5 (169.0, 260.8) −0.705 0.481

LZD, linezolid; LIT, LZD-induced thrombocytopenia; Non-LIT, non-LZD-induced thrombocytopenia; GA, gestational age; PNA, postnatal age; BW, birth weight; PLT, platelet.