TABLE 2.
Characteristics | Value | LIT group (n = 9) | Non-LIT group (n = 30) | T/Z | p value |
---|---|---|---|---|---|
Gender | — | — | — | — | — |
Female, n (%) | 14 (35.9) | 4 (44.4) | 10 (33.3) | — | 0.696 |
Male, n (%) | 25 (64.1) | 5 (55.6) | 20 (66.7) | ||
GA (w), (mean ± SD) | 31.3 ± 3.7 | 28.8 ± 3.3 | 32.0 ± 3.5 | −2.463 | 0.019 |
PNA (d), median (IQR) | 12.0 (7.0, 20.0) | 10.0 (3.0, 26.5) | 12.5 (8.8, 19.3) | −0.818 | 0.413 |
BW (g), median (IQR) | 1350.0 (1000.0, 1850.0) | 880.0 (760.0, 1360.0) | 1525.0 (1200.0, 1900.0) | −2.836 | 0.005 |
Weight at medication (g), median (IQR) | 1560.0 (1190.0, 1990.0) | 840.0 (745.0, 1785.0) | 1630.0 (1295.0, 2075.0) | −2.584 | 0.008 |
Duration of LZD treatments (d), median (IQR) | 10.0 (9.0,12.0) | 12.0 (8.0, 14.0) | 10.0 (8.8, 11.0) | −1.197 | 0.231 |
PLT (×109/L), median (IQR) | 206.0 (169.0, 267.5) | 236.0 (139.0, 312.0) | 201.5 (169.0, 260.8) | −0.705 | 0.481 |
LZD, linezolid; LIT, LZD-induced thrombocytopenia; Non-LIT, non-LZD-induced thrombocytopenia; GA, gestational age; PNA, postnatal age; BW, birth weight; PLT, platelet.