Table 3.

Analysis of Brigham and Woman’s Hospital staging systems’ accuracy in determining appropriate risk assessment

Study	Understaged (% of metastases occurring in patients deemed low risk)a	Overstaged (% of high-risk cases without metastasis over-called)b
Tschetter et al. (2020) [35]	60.0	94.1
Ruiz et al. (2019) [61]	30.4	74.6
Marrazzo et al. (2018) [36]	22.6	83.4
Cañueto et al. (2018) [60]	39.1	73.1
Haisma et al. (2016) [22]	51.9	64.3
Karia et al. (2014) [62]	31.3	76.1
Jambusaria-Pahlajani et al. (2013) [19]	16.0	61.8
Median	31.3	74.6
Average	35.9	75.3
Comprehensive	35.1	75.7

^aPatients with metastatic outcomes initially staged as T1 or T2a (% = metastatic case T1 or T2a/total metastatic cases)

^bPatients without metastatic outcomes initially staged as T2b or T3 (% = event free cases T2b or T3/total cases T2b or T3)