Why carry out this study?

Acne vulgaris (acne) is chronic inflammatory dermatosis with multifactorial etiology, affecting mainly adolescents.

Common therapies such as antibiotic and retinoids, both topical and oral, have many limitations. In this view, treatments other than topical and systemic antibiotics are needed to restore the dysbiosis correlated with acne onset and evolution.

What was learned from the study?

The results from this study suggest that the administration of a dietary supplement containing B. breve BR03, L. casei LC03, L. salivarius LS03, lupeol and Echinacea extract in subjects with mild to moderate facial acne is safe, well tolerated, and able to reduce total facial lesion count (GAGS score) versus placebo and probiotics and botanical extracts alone after 8 weeks of administration.