Fig. 5.

Adjusted mean change in PASI total score from baseline (baseline treatment cohort). Error bars represent SE. Analysed using MMRM model including baseline treatment cohort, psoriatic arthritis, visit as fixed effect factors, baseline PASI total score value as covariate and the baseline treatment cohort by visit interaction, psoriatic arthritis by visit interaction, and baseline PASI total score by visit interaction. ^†Other biologics versus conventional systemics; *secukinumab versus conventional systemics. FAS3/6/12 full analysis set at month 3, 6 or 12; LS least squares; PASI, Psoriasis Area and Severity Index; MMRM mixed model repeated measures; SE standard error