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. 2022 Feb 16;13:886. doi: 10.1038/s41467-022-28551-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Head-direction polar plots; peak firing rate (F.R) (top-left), mean resultant length (MRL) (top-right). MRL (nTG-y-nTG-a: P = 0.051; nTG-y-APP-y: P = 0.45; APP-y-APP-a: P = 0.41; nTG-a-APP-a: P = 0.11), peak F.R (nTG-y-nTG-a: P = 0.44; nTG-y-APP-y: P = 0.21; APP-y-APP-a: P = 0.96; nTG-a-APP-a: P = 0.073), mean F.R (nTG-y-nTG-a: P = 0.18; nTG-y-APP-y: P = 0.28; APP-y-APP-a: P = 0.87; nTG-a-APP-a: P = 0.08). n = 295 nTG-y; 244 nTG-a; 305 APP-y; 471 APP-a. b Non-grid spatially tuned rate maps; peak F.R (top-left), split-half-reliability (top-right). Field size (nTG-y-nTG-a: P = 0.40; nTG-y-APP-y: P = 0.66; APP-y-APP-a: P = 0.64; nTG-a-APP-a: P = 0.37), peak F.R (nTG-y-nTG-a: P = 0.028; nTG-y-APP-y: P = 0.49; APP-y-APP-a: P = 0.73; nTG-a-APP-a: P = 0.032), mean F.R (nTG-y-nTG-a: P = 0.76; nTG-y-APP-y: P = 0.37; APP-y-APP-a: P = 0.50; nTG-a-APP-a: P = 0.93). n = 82 nTG-y; 83 nTG-a; 106 APP-y; 119 APP-a. c Place cell rate maps; peak F.R (top-left), spatial information (S.I) (top-right). S.I (P = 0.08), peak F.R (P = 0.32), mean F.R (P = 0.31). n = 118 nTG-a; 109 APP-a. d S.I (P left-to-right: 0.03; 0.03; 0.028; 0.057; 0.10; 0.15; 0.16; 0.28; 0.18; 0.12; 0.08; 0.16; 0.11; 0.12; 0.30; 0.31; 0.41), mean F.R (P left-to-right: 0.64; 0.64; 0.70; 0.81; 0.95; 0.99; 0.90; 0.82; 0.85; 0.73; 0.31; 0.24; 0.048; 0.016; 0.025; 0.027; 0.039) when varying peak F.R criterion. (nTG-a n left-to-right: 210; 210; 209; 205; 197; 187; 172; 159; 147; 136; 118; 103; 91; 83; 75; 61; 56. APP-a n left-to-right: 233; 233; 231; 224; 212; 202; 185; 166; 148; 127; 109; 94; 77; 62; 54; 49; 45) e MEC theta frequency and power versus running speed. Data are mean ± 99% confidence intervals. Wilcoxon rank-sum tests (two-sided) with Bonferroni-Holm’s correction were applied to panels a–d. Data in bar graphs are medians ± 25th and 75th percentiles; Boxplots present medians as dots, interquartile boxes from 25th to 75th percentile, whiskers from smallest to largest values; *P < 0.05; n.s not significant. Source data are provided as a Source Data file.