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. 2022 Feb 3;9:817911. doi: 10.3389/fcvm.2022.817911

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Copyright © 2022 Lyu, Pan, Li, Li, Yang, Dong, Guo, Lin, Han, Liang, Sun, Yu, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between hyperemic MBF and severity of stenosis. Bar plots shows (A) hyperemic MBF for vessel territories with server stenosis (DS > 90%) was significantly lower compared with vessel territories without significant stenosis (DS < 30%) and vessel territories with intermediate stenosis (DS 30–90%) at ICA. (B) Hyperemic MBF of non-ischemic myocardium was significantly lower than ischemic myocardium defined by ICA/FFR. (C) Hyperemic MBF was significantly lower in vessels with FFR of ≤ 0.80 compared with that in vessels with FFR > 0.80. DS, diameter stenosis; FFR, fractional flow reserve; ICA, invasive coronary angiography; MBF, myocardial blood flow.