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. 2022 Feb 3;8:812631. doi: 10.3389/fcvm.2021.812631

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Copyright © 2022 Baoqi, Dan, Xingxing, Xueqing, Yajing, Ke and Liyun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Therapeutic drugs for RA are a double-edged sword in case of RA-induced CVDs. Some drugs may reduce the incidence of CVDs in patients with RA by inhibiting inflammation and improving endothelial function and insulin resistance, and some drugs may impair the mechanism of vascular repair, have harmful effects on the cardiovascular system, and increase the risk of developing CVDs. We will explain the effects of these drugs on the cardiovascular risk of patients with RA.