Table 1.

Summary of tumor suppressor miRNAs in pancreatic cancer.

miRNA	Function	Target gene	Author	Publication year
miR-429	Increase chemosensitivity to gemcitabine	PDCD4	Yu et al[3]	2017
miR-205	Inhibit proliferation, invasion, migration, and increase chemosensitivity to gemcitabine	Not mentioned	Chaudhary et al[4]	2017
miR-217	Inhibit proliferation, invasion, and promote apoptosis	E2F3	Yang et al[5]	2017
	Inhibit invasion and migration	ANLN	Idichi et al[6]	2017
	Inhibit proliferation, invasion, and migration	Tpd52l2	Chen et al[7]	2017
miR-221	Induce autophagy and apoptosis	HDAC6	Yang et al[8]	2018
	Inhibit proliferation	SOCS3	Xie et al[9]	2018
miR-876-3p	Inhibit proliferation, invasion, migration, and promote apoptosis	JAG2	Yang et al[10]	2018
miR-675	Inhibit proliferation	E2F-1	Ma et al[11]	2018
miR-98-5p	Inhibit proliferation, invasion, and metastasis	MAP4K4	Fu et al[12]	2018
miRNA-339-5p	Inhibit invasion and migration	ZNF689	Yu et al[13]	2019
miR-142-5p	Inhibit proliferation and promote apoptosis	RAP1A	Yao et al[14]	2019
miRNA-33b	Inhibit proliferation, invasion, andmigration	MMP16	Luo et al[15]	2020
miR-4516	Inhibit proliferation, invasion, migration, and promote apoptosis	OTX1	Chen et al[16]	2020

miRNAs: MicroRNAs; SOCS3: suppressor of cytokine signaling 3.