Skip to main content
. 2021 Nov 24;135(1):4–10. doi: 10.1097/CM9.0000000000001826

Table 2.

Summary of oncogenic miRNAs in pancreatic cancer.

miRNA Function Target gene Author Publication year
miR-196a Promote proliferation, invasion, and migration, and inhibit apoptosis ING5 Liu et al[29] 2013
miR-221 Promote proliferation PTEN, p27kip1, p57kip2, and PUMA Sarkar et al[30] Yang et al[31] 2013 2016
miR-371-5p Promote proliferation ING1 He et al[32] 2014
miR-301b Promote invasion, migration, and resistance to gemcitabine TP63 Funamizu et al[33] 2014
miR-221-3p Promote proliferation, invasion, migration, and resistance to 5-FU RB1 Zhao et al[34] 2016
miR-451 Promote proliferation and migration CAB39 Guo et al[35] 2017
miR-301a-3p Increase chemoresistance to gemcitabine PTEN Xia et al[36] 2017
miR-106b Increase chemoresistance to gemcitabine TP53INP1 Fang et al[37] 2019
miR-302a-3p Promote invasion and migration SOCS5 Zhang et al[38] 2019
miR-132 Promote proliferation and inhibit apoptosis Shh Zhao et al[39] 2019
miR-132 Promote proliferation, invasion, and migration PTEN Zhang et al[40] 2019
miR-210 Increase chemoresistance to gemcitabine Not mentioned Yang et al[41] 2020
miR-193a-5p Promote invasion and migration SRSF6 Li et al[42] 2020

miRNAs: MicroRNAs; 5-FU: 5-fluorouracil.