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. 2021 Oct 18;135(1):52–62. doi: 10.1097/CM9.0000000000001768

Table 2.

Associations between discharge heart rate groups and 1-year clinical outcomes in the entire cohort.

Outcomes Event rate (%) Unadjusted HRs (95% CI) P-value Adjusted HRs (95% CI) P value
Composite outcome of all-cause death and HF readmission (primary outcome)
 <65 bpm 53.0 1.39 (1.12–1.72) 0.003 1.32 (1.05–1.68) 0.020
 65–85 bpm 42.5 1.00 (reference) NA 1.00 (reference) NA
 ≥86 bpm 49.8 1.34 (1.11–1.62) 0.002 1.34 (1.07–1.67) 0.009
All-cause death∗
 <65 bpm 19.1 0.98 (0.65, 1.47) 0.924 0.76 (0.50, 1.15) 0.191
 65–85 bpm 16.2 1.00 (reference) NA 1.00 (reference) NA
 ≥86 bpm 20.8 1.35 (0.98, 1.87) 0.067 1.14 (0.82, 1.60) 0.433
HF readmission
 <65 bpm 40.9 1.28 (1.02–1.61) 0.033 1.14 (0.88–1.46) 0.327
 65–85 bpm 34.0 1.00 (reference) NA 1.00 (reference) NA
 ≥86 bpm 36.3 1.14 (0.92–1.41) 0.232 1.16 (0.91–1.47) 0.238
Composite outcome of all-cause death and all-cause readmission
 <65 bpm 57.7 1.29 (1.06–1.56) 0.010 1.25 (1.02–1.54) 0.034
 65–85 bpm 49.4 1.00 (reference) NA 1.00 (reference) NA
 ≥86 bpm 49.8 1.17 (0.97–1.40) 0.093 1.23 (1.01–1.49) 0.044

Proportional hazards assumptions were satisfied for the primary outcome, HF readmission, and composite outcome of all-cause death and all-cause readmission, but not for all-cause death. ∗HRs for all-cause death pertain to a 250-day follow-up period; all other HRs are based on the entirety of 1-year follow-up. Bpm: Beats per minute; CI: Confidence interval; HR: Hazard ratio; HF: Heart failure.