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Close-up view of the interactions between SARS-CoV-2 Mpro with ML188 derivative 23R and perampanel derivative 26. Close-up view of the interactions between SARS-CoV-2 Mpro and inhibitors in crystal structures. Mpro is shown as cartoon representation, with residues involved in the interaction shown as sticks. Inhibitors are shown as violet sticks. Hydrogen bonds were labeled with dashed lines. (A) Compound 23R (PDB: 7KX5), violet. (B) Compound 26 (PDB: 7L14), orange.
