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. 2022 Feb 19;12:04011. doi: 10.7189/jogh.12.04011

Table 3.

Neonatal deaths by gestational age at birth, overall and by region

Overall
Live births whose vital status at the end of neonatal period is known
9884
Neonatal deaths
289 (29/1000 LB)
Proportion of preterm deaths among all neonatal deaths
46.4%
Proportion of preterm infants who died during neonatal period
13.8%
Gestational age* in completed week (gestational age available n = 9884)
Neonatal deaths
OR (95% CI)
Adjusted OR(95% CI)
P-value
<32 weeks (n = 98)
61 (62.2%)
98.4 (63.3, 152.9)
108.2 (52.1, 224.1)

32 to <34 weeks (n = 144)
30 (20.8%)
15.7 (10.2, 24.3)
13.7 (6.9, 27.2)

34 to <37 weeks (n = 732)
43 (5.9%)
3.7 (2.6, 5.3)
3.6 (2.1, 6.3)
P < 0.001
37 to <42 weeks (n = 8556)
141 (1.7%)
1.0 (reference)
1.0 (reference)

≥42 weeks (n = 354)
14 (4.0%)
2.5 (1.4, 4.3)
1.9 (0.67, 5.4)

Asia
Live births whose vital status at the end of neonatal period is known
5563
Neonatal deaths
201 (36.1/1000 LB)
Proportion of preterm deaths among all neonatal deaths
49.3%
Proportion of preterm infants who died during neonatal period
13.2%
gestational age* in week (gestational age available n = 5563)
Neonatal deaths
OR (95% CI)
Adjusted OR(95% CI)
P-value
<32 weeks (n = 69)
45 (65.2%)
93.1 (54.4, 159, 2)
162.2 (61.5, 427.7)

32 to <34 weeks (n = 109)
18 (16.5%)
9.8 (5.7, 17.0)
9.8 (4.1, 23.5)

34 to <37 weeks (n = 574)
36 (6.3%)
3.3 (2.2, 4.9)
4.0 (2.1, 7.6)
P < 0.001
37 to <42 weeks (n = 4712)
93 (2.0%)
1.0 (reference)
1.0 (reference)

≥42 weeks (n = 99)
9 (9.1%)
4.7 (2.4, 10.2)
3.0 (0.7, 13.2)

Africa
Live births whose vital status at the end of the neonatal period is known
4321
Neonatal deaths
88 (20.4/1000 LB)
Proportion of preterm deaths among all neonatal deaths
39.8%
Proportion of preterm infants who died during neonatal period
15.8%
Gestational age* in week (gestational age available n = 4321)
Neonatal deaths
OR (95% CI)
Adjusted OR(95% CI)
P-value
<32 weeks (n = 29)
16 (55.2%)
97.3 (44.4, 213.5)
65.7 (17.8,242.2)

32 to <34 weeks (n = 35)
12 (34.3%)
41.3 (19.4, 87.7)
39.5 (10.6, 146.0)

34 to <37 weeks (n = 158)
7 (4.4%)
3.7 (1.6, 8.2)
2.7 (0.8, 9.3)
P < 0.001
37 to <42 weeks (n = 3844)
48 (1.3%)
1.0 (reference)
1.0 (reference)

≥42 weeks (n = 255) 5 (2.0%) 1.6 (0.6, 4.0)
1.3 (0.3, 5.4)

OR – odds ratio, CI – confidence interval

*Gestational age is based on ultrasound.

†OR was adjusted for site, mother's age, mother's education, wealth quintile and previous obstetric history, including previous stillbirth and previous preterm birth, morbidity during pregnancy (antepartum haemorrhage, pre-eclampsia and eclampsia, antepartum fever) and multiple gestations.