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. 2022 Feb 3;8:771859. doi: 10.3389/fmed.2021.771859

Table 1.

Details of included studies.

References Type Location Type of surgery Protocol for nerve block Sample size Mean/median age (years) Male gender (%) Surgery duration (min) Post-operative analgesic drugs
QLB Control QLB Control QLB Control QLB Control
Wilson et al. (32) RCT USA Arthroscopy Pre-operative USG guided lateral QLB with 40 ml of 0.25% ropivacaine 22 24 29.8 37.1 36.4 41.7 149.9 ± 53.1 163.6 ± 51.1 Oxycodone, IV hydromorphone
Haskins et al. (33) RCT USA Arthroscopy Pre-operative USG guided anterior QLB with 30 ml of 0.5% bupivacaine and 2 mg of dexamethasone 48 48 36 36 50 45.8 95 ± 23 95 ± 33 Oxycodone, PCM and naproxen/indomethacin and IV hydromorphone as rescue analgesic
Brixel et al. (31) RCT France Arthroplasty Pre-operative USG guided posterior QLB with 30 ml of 0.33% ropivacaine 50 50 68 65 60 40 70 (63–77) 68 (61–81) IV PCM, IV ketoprofen, and morphine PCA
Yuan et al. (29) RCT China Arthroscopy Pre-operative USG guided posterior QLB with 0.4% ropivacaine 40 40 36.7 36.5 47.4 50 80.8 ± 8.1 82.5 ± 9.3 Sufentanil PCA, oral PCM and diclofenac
He et al. (30) RCT China Arthroplasty Pre-operative USG guided posterior QLB with 0.33% ropivacaine 44 44 66 67 29.5 25 98 ± 8 100 ± 7 IV parecoxib, oral PCM, and morphine PCA
Abduallah et al. (28) RCT Egypt Arthroplasty Post-operative USG guided posterior QLB with 30 ml of 0.25% bupivacaine 30 30 67.9 66.4 30 36.7 122 ± 9.2 125 ± 4.6 IV PCM and morphine rescue analgesic
Kukreja et al. (25) R USA Arthroplasty Pre-operative USG guided posterior QLB with 20 ml of 0.25% bupivacaine 79 159 NR NR NR NR NR NR NR
Kukreja et al. (26) RCT USA Arthroplasty Pre-operative USG guided anterior QLB with 30 ml of 0.25% bupivacaine 36 35 58.6 58 44.4 57.1 NR NR NR
Kinjo et al. (27) R USA Arthroscopy Pre-operative USG guided anterior QLB with 20–30 ml of 0.33–0.5% ropivacaine 15 54 35 35 33 55 97 ± 22.6 89 ± 20.1 NR
Tulgar et al. (24) RCT Turkey Hip and proximal femur surgery Pre-operative USG guided posterior QLB with 20 ml of 0.5% bupivacaine and 10 ml of 2% lidocaine 20 20 68.7 68.7 25 25 107 ± 19.9 110 ± 21.3 IV PCM and tramadol PCA, IV fentanyl and IM diclofenac as rescue analgesic
McCrum et al. (23) R USA Arthroscopy Pre-operative USG guided anterior QLB with 20–30 ml of 0.5% ropivacaine, 20–30 mcg of dexmedetomidine and 4 mg dexamethasone 28 28 37 36 39.3 28.6 74 ± 34 69 ± 20 IV PCM, IV ketorolac, and IV hydromorphone as rescue analgesic
He et al. (21) RCT China Arthroplasty Post-operative USG guided posterior QLB with 30 ml of 0.33% ropivacaine 30 30 64 65 46.7 43.3 91 ± 21 96 ± 19 Sufentanil PCA
Stuart Green et al. (22) R USA Arthroplasty Pre-operative USG guided QLB with 30 ml of 0.5% ropivacaine 10 10 NR NR NR NR NR NR NR

IV, intravenous; IM, intramuscular; R, Retrospective; RCT, randomized controlled trial; PCM, paracetamol; PCA, patient controlled analgesia; NR, not reported; QLB, quadratus lumborum block; USG, ultrasound.