TABLE 2.
Comparisons between cow's milk and the other culprit foods, in terms of age at the onset of the first symptoms, first OFC, and resolution
| Cow's milk (n = 108) | Solid foods (n = 83) | Hen's egg (n = 29) | Fish (n = 21) | Vegetables, legumes and fruits (n = 21) | Rice (n = 6) | Meat (n = 5) | |
|---|---|---|---|---|---|---|---|
| Age at first symptoms (months) | 3.0 (1–5.3) | 8.0 (6.0–12.0)* | 8.0 (6.0–9.0)* | 8.0 (6.0–12.5)* | 10.5 (7.8–12.3)* | 5.0 (4.3–5.8) | 11.1 (9.5–14.8)** |
| (n = 107) | (n = 76) | (n = 27) | (n = 19) | (n = 20) | (n = 6) | (n = 4) | |
| Age at first OFC (years) | 1.8 (1.3–2.5) | 2.6 (1.9–3.3)* | 1.9 (1.7–2.8) | 3.0 (2.6–5.2)* | 2.6 (2.1–3.1)** | 1.9 (1.4–2.7) | 5.3 (4.3–6.2)** |
| (n = 105) | (n = 67) | (n = 26) | (n = 16) | (n = 17) | (n = 5) | (n = 3) | |
| Tolerant patients | 95 (88.0%) | 56 (67.5%) | 24 (82.8%) | 11 (52.4%) | 14 (66.7%) | 5 (83.3%) | 2 (40.0%) |
| Age of tolerance (years) | 2.0 (1.5–2.9) | 2.6 (1.9–3.0)*** | 2.2 (1.8–2.8) | 2.9 (2.3–4.5)*** | 2.6 (2.0–3.1) | 1.9 (1.4–2.7) | 5.2 (4.2–6.1) |
| (n = 95) | (n = 55) | (n = 24) | (n = 11) | (n = 13) | (n = 5) | (n = 2) |
Note: Age expressed in median months or years (interquartile range). OFC: Oral Food Challenge. Comparison between cow's milk and the other foods, except for difference between tolerance for milk and meat (“Meat” group too low).
*p < 0.001; **p < 0.01; ***p < 0.05.