TABLE 4.

Outcomes of first OFC according to different factors

Univariate analysis
	Success (n = 129)	Failure (n = 44)	RR [IC95%]	p value
Age at first symptoms (years)	0.4 [0.3–0.7]	0.4 [0.1–0.7]		0.4
Age at first OFC (years)	2.1 [1.6–3.0]	1.7 [1.2–2.7]		0.6
Delay between first symptoms and first OFC	1.5 [1.1–2.3]	1.3 [0.9; 2.1]		0.7
OFC performed in the first year after first symptoms	23/128 (17.9%)	15/43 (34.8%)	1.3 [1.0–1.7]	0.02
Age at tolerance	2.1 [1.6–3.0]	2.3 [1.9–3.8]		0.1
History of severe reaction(s)	1 (0.8%)	10 (22.7%)	4.3 [3.0–6.2]	<0.001
Positive culprit food specific IgE	19/122 (15.6%)	9/42 (21.4%)		0.4
Chronic FPIES	34/118 (28.8%)	11/42 (26.2%)		0.8
Multiple FPIES	11 (8.5%)	4 (9.1%)		1
Personal atopic history	53/120 (44.2%)	16/42 (38.1%)		0.5
Familial atopic history	80/121 (66.1%)	27/43 (62.7%)		0.7

Multivariate analysis
	OR [IC95%]	p value
OFC Performed in the first year after first symptoms	2.6 [1.1–6.6]	0.04
History of severe reaction(s)	40 [4.8–333.3]	<0.001

Note: The bold numbers indicates p < 0.05.