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. 2022 Feb 3;9:790047. doi: 10.3389/fcell.2021.790047

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Copyright © 2022 Sun, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The results of consensus clustering of ferroptosis-related genes with gene set variation analysis (GSVA) enrichment analysis. (A) The heatmap showed the detailed clinicopathological features of skin cutaneous melanoma (SKCM) patients in each cluster. (B) SKCM patients were divided into three clusters according to the consensus clustering (k = 3). (C) TP53 mutation state in each cluster. GSVA enrichment analysis revealed the top 20 significant biological pathways between every two clusters: (D) cluster A vs. cluster B, (E) cluster B vs. cluster C, and (F) cluster A vs. cluster C.