Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 3;13:830791. doi: 10.3389/fphar.2022.830791

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Liao, Li, Huang, Yu, Chen, Gan, Xiao, Xiang, Ding, Jiang, Li and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Mean plasma concentration of HSK3486 after intravenous bolus injection in rats. Data are mean ± SD (n = 6). Rats in each group received HSK3486 at 1, 2, or 4 mg/kg in an injection volume of 0.5 ml/kg. Blood samples were obtained from each animal at pre-dose and at 2, 4, 8, 12, 20, 30, 60, 90, 120, and 360 min after the dose. Samples were placed in tubes containing K2EDTA and stored on ice until centrifuged to separate plasma. Plasma samples were stored frozen at approximately −70°C until analyzed by a validated method for HSK3486.