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Mean plasma concentration of HSK3486 by time after intravenous bolus injection in beagle dogs. Data are mean ± SD (n = 6). Dogs (3/sex/group) were given HSK3486 at doses of 1, 2, or 4 mg/kg by IV injection. Blood samples were obtained from each animal at pre-dose and at 2, 4, 8, 12, 20, 30, 60, 90,120, 240, and 360 min after the dose.
