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Summary of intra-epidermal nerve fiber density (IENFD)
Skin biopsies were collected prior to treatment and at necropsy, sectioned, and stained using Protein Gene Product 9.5. Axons were counted as they crossed the dermal/epidermal junction, and the number of axons per linear millimeter of epidermal/dermal junction was calculated. Bars represent mean and SD; the gray shaded area represents the range of pretreatment values from samples collected.
