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. 2022 Feb 3;13:792755. doi: 10.3389/fmicb.2022.792755

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Copyright © 2022 Gu, Zheng, Sun and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of purified antimicrobial agents on ROS levels and cell integrity of P. aeruginosa PAO1 and MRSA under fluorescence microscopy. (A) Effects of fengycin on ROS accumulation (a,b) and cell membrane damage (c,d) of P. aeruginosa PAO1. (B) Effects of surfactin on ROS accumulation (a,b) and cell membrane damage (c,d) of MRSA cells. The bacterial cells in the test group were treated with the antimicrobial agents at the final concentration of 200 μg/ml, that were dissolved in methanol, and the bacterial cells in the control group were treated with the same amount of methanol.