Characterization of stem cell-derived EVs. (A) Protein concentrations. (B) Lipid concentrations. (C) Morphological analysis by TEM of EVs derived from PSCs and BMSCs at D0, D7, and D21. (D) Average hydrodynamic diameters of EVs measured by DLS analysis. All data are represented as mean ± SD. * indicates p < 0.05. BMSC, bone marrow-derived mesenchymal stem cell; DLS, dynamic light scattering; EV, extracellular vesicle; PSC, placental stem cell; SD, standard deviation; TEM, transmission electron microscopy. Color images are available online.