Multivariated statistical analysis based on Count-Per-Millon (CPM) data. (A) PLS-DA score plot of LP1, LP2, and LP3 group in metabolomics (positive ion mode) analysis. (B) Permutation test plot of LP1, LP2, and LP3 group in metabolomics analysis. The x-axis represents the correlation coefficient between the original y-variable and the permuted y-variable, the y-axis represents the cumulative R2 and Q2 of the correlation coefficient. (C) PLS-DA score plot of LP1, LP2, and LP3 group in transcriptome analysis. (D) Permutation test plot of LP1, LP2, and LP3 group in transcriptome analysis. The x-axis represents the correlation coefficient between the original y-variable and the permuted y-variable, the y-axis represents the cumulative R2 and Q2 of the correlation coefficient.