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. 2022 Jan 29;25(2):103833. doi: 10.1016/j.isci.2022.103833

Figure 1.

Figure 1

Expression of Abi1 is upregulated in asthmatic human airway smooth muscle (HASM) cells

(A and B) Abi1 mRNA in nonasthmatic HASM cultures (n = 24) and asthmatic HASM cultures (n = 21) was evaluated by RT-qPCR. Abi1 mRNA is upregulated in 10 of 21 asthmatic cultures.

(C and D) Abi2 mRNA is similar between nonasthmatic and asthmatic cultures. mRNA normalization is calculated using the following formula: Abi1 RQ (relative quantification) of individual cell culture line divided by the means of Abi1 RQ of all control cell cultures.

(E and F) Abi1 protein in HASM cultures was determined using ELISA. Abi1 protein is enhanced in asthmatic ASM cultures with increased Abi1 mRNA expression.