Table 1. Characteristics of Patients in the Nanjing and JHH Cohortsa.
Characteristic | Nanjing cohort | JHH cohort | |||
---|---|---|---|---|---|
Patients with PDAC (n = 1009) | Patients with non-PDAC diseases (n = 885) | Patients who underwent pancreatectomy (n = 939) | Patients with PDAC (n = 854) | Patients with non-PDAC diseases (n = 339) | |
Age, y | |||||
Mean (SD) | 62.8 (10.2) | 52.0 (15.9) | NA | 65.0 (10.9) | 60.1 (14.1) |
Median (range) | 65 (16-82) | 65 (10-85) | NA | NA | NA |
Sex | |||||
Female | 382 (37.9) | 408 (46.1) | NA | 399 (46.7) | 158 (46.6) |
Male | 627 (62.1) | 477 (53.9) | NA | 455 (53.3) | 181 (53.4) |
Disease | |||||
PDAC | 690 (68.4) | NA | NA | 854 (100) | NA |
Acute pancreatitis | NA | 355 (37.8) | 0 | NA | NA |
Chronic pancreatitis | NA | 98 (11.1) | 65 (6.9) | NA | NA |
Ampullary carcinoma | NA | 31 (3.5) | 29 (3.1) | NA | NA |
Cholangiocarcinoma | NA | 35 (3.9) | 26 (2.8) | NA | 47 (13.9) |
Duodenal adenocarcinoma | NA | 34 (3.8) | 32 (3.4) | NA | 54 (15.9) |
Pancreatic neuroendocrine tumor | NA | 119 (13.4) | 112 (11.9) | NA | NA |
Gastrointestinal stromal tumor | NA | 11 (1.2) | 9 (1.0) | NA | NA |
Intraductal papillary mucinous neoplasm | NA | 70 (7.9) | 67 (7.1) | NA | NA |
Mucinous cystic neoplasm | NA | 44 (5.0) | 43 (4.6) | NA | NA |
Serous cystic neoplasm | NA | 32 (3.6) | 28 (3.0) | NA | NA |
Solid pseudopapillary tumor | NA | 56 (6.3) | 56 (6.0) | NA | 4 (1.2) |
History of other cancers | 32 (3.2) | 14 (1.6) | NA | NA | NA |
First-degree relative with pancreatic cancer | 9 (0.9) | 0 | NA | 77 (9.0) | NA |
Abbreviations: JHH, Johns Hopkins Hospital; NA, not available; PDAC, pancreatic ductal adenocarcinoma.
Data are presented as the number (percentage) of individuals unless otherwise indicated.